Aptamers are single-stranded oligonucleotides generated by the systematic evolution of ligands by exponential enrichment (SELEX). They have a wide variety of applications, but computational approaches are necessary to efficiently identify candidate aptamers. A team of researchers has now developed RaptGen, a variational autoencoder that efficiently discovers new aptamers not included in the input SELEX dataset. This novel computational model could one day be the standard method for aptamer generation.
from Latest Science News -- ScienceDaily https://ift.tt/ywXeUEs
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