For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how chromosomes change shape during cell division. Certain protein complexes help fold DNA into overlapping loops that repel each other, which then stack to create a rod-like structure. This is the first time scientists have directly observed an entire chromosome in high resolution within a dividing cell, offering new insights into how chromosomes are formed.
from Latest Science News -- ScienceDaily https://ift.tt/am8DsGp
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